The use of fibrin glue in abdominal and pediatric surgery is established procedure. In recent years, further areas of application and other indications have been added to the list: high risk anastomosis, as a protective measure in vascular anastomosis (especially after liver transplantation), in the treatment of fistulas - in particular lymphatic fistulas. In pediatric surgery fibrin glue is used mainly in orthotopic liver transplantation and in operations involving the parenchymal organs such as liver, spleen, pancreas, and kidney.