Synaptic Constituents in Health and Disease

Synaptic Constituents in Health and Disease is a collection of papers from the Proceedings of the Third Meeting of the European Society for Neurochemistry held in Yugoslavia, on August 31-September 5, 1980. This collection deals with gene analysis, the diagnosis, and treatment of inherent errors in metabolism. One paper discusses the role of vesicles in cholinergic systems in terms of the vesicle hypothesis or the cytosol hypothesis. Another paper focuses on the molecular organization of chromaffin granulles-the catecholamine-storing vesicles of the adrenal medulla. One author discusses the interaction between antibodies and receptors in receptors such as insulin, TSH, prolactin, or estrogens. Another paper examines the occurrence and postulated functions of trans-synaptic structures to find out whether some kind of structural continuity exists, beyond mere contact, between the plasma membranes of two synapsing neurons. One other paper shows that morphological evidences of damage on nerve cells in some brain areas are found after gerbils inhaling an industrial solvent, trichloroethylene (TCE), The paper also discusses general topics in neurochemistry such as the DNA turnover in rat cerebral cortex. This collection can prove invaluable for biologists, medical and chemical researchers, molecular scientists, and the neuro-chemist investigators.