Platelet Biology: Implications in Health and Disease

Platelets or thrombocytes are small, disc-shaped cell fragments found in the blood. They play a crucial role in maintaining hemostasis, inflammation and wound healing. Platelet biology is the study of thrombocytes, their structure and functions. Platelets release cytokines, chemokines, and growth factors, fostering communication between various cell types and modulating immune responses. Platelets interact with leukocytes, endothelial cells, and pathogens, influencing vascular integrity and immune surveillance. Dysregulation of platelet function underlies various pathological conditions, including thrombosis, atherosclerosis, and inflammatory disorders. Understanding platelet biology is therefore crucial for developing therapeutic strategies to manage cardiovascular diseases, immune disorders, and other health challenges. This book is a compilation of chapters that discuss the most vital concepts and emerging trends in the field of platelet biology. From theories to research to practical applications, case studies related to all contemporary topics of relevance to this field have been included herein. As this field is emerging at a rapid pace, the contents of this book will help the readers understand the modern concepts and applications of the subject.