Vogt-Koyanagi-Harada disease

Vogt-Koyanagi-Harada disease is an autoimmune inflammatory disease characterized by bilateral granulomatous panuveitis, associated with neurological, auditory and integumentary manifestations.Ocular involvement consists mainly of multiple retinal serous detachments, characteristic of the early stage, and depigmentation of the fundus, giving a "sunset" appearance characteristic of the late stage of the disease. Diagnosis is generally straightforward, based on a careful ophthalmological examination. Multimodal imaging plays an important role, not only in the diagnosis of doubtful cases, but above all in monitoring and assessing the prognosis of the disease. The prognosis is generally good, provided the diagnosis has been made in good time and treatment promptly initiated.