Steroidal Activity in Experimental Animals and Man

Methods in Hormone Research, Volume IV: Steroidal Activity in Experimental Animals and Man, Part B focuses on protection against irradiation damage, anti-mammary tumor activity, anti-androgens, steroids, and anti-progestational compounds. The selection first offers information on the thermogenic properties of steroids and anabolic steroids, as well as characteristics of steroid pyrogen action in man; species specificity of steroid pyrogen action; clinical significance of thermogenic steroids; and relative activity of anabolic steroids in animals and man. The book also ponders on anti-androgens and anti-progestational compounds. The manuscript examines steroids in reactivated prostatic cancer and tumorigenesis in experimental animals. Discussions focus on treatment and nature of relapse, cooperative study program, mammary and pituitary tumors, testicular interstitial cell tumors, and neoplasms of the female genital tract. The text then elaborates on inhibition of tumor growth by steroids and the effect of corticoids and ACTH on the induction of gastric ulcers in laboratory animals. The selection is a dependable reference for readers interested in steroidal activity in man and animals.