This book is the first volume that provides an unique overview of the most recent and relevant contributions in the field of mathematical physics with a focus on the mathematical features of quantum mechanics. It is a collection of review papers together with brand new works related to the activities of the INdAM Intensive Period "e;INdAM Quantum Meetings (IQM22)"e;, which took place at the Politecnico di Milano in Spring 2022 at Politecnico di Milano. The range of topics covered by the book is wide, going ranging from many-body quantum mechanics to semiclassical analysis, quantum field theory, Schrodinger and Dirac operators and open quantum systems