Ovarian Hyperstimulation Syndrome

Ovarian hyperstimulation syndrome (OHSS) is a serious and potentially life-threatening complication of ovarian stimulation in women undergoing in vitro fertilization (IVF). It is triggered solely by human chorionic gonadotrophin (hCG), used for final oocyte maturation (early OHSS), or by endogenous hCG produced by the implanted blastocyst (late OHSS). Although its incidence may have decreased due to advances in ovarian stimulation protocols, OHSS remains a significant concern in the context of rising global ART cycles. This text, authored by eminent international experts, comprehensively explores OHSS, with a focus on prevention, complications, and treatment strategies, incorporating the latest scientific advances.

• Offers a state-of-the-art overview of all clinical aspects of OHSS
• Provides focused OHSS guidance for gynecologists, reproductive specialists and healthcare professionals
• Highlights the role of modern ovarian stimulation protocols in reducing OHSS