This volume illustrates contemporary lines of investigation and potential development of angiogenic mechanisms. The main themes that dominate this research field are, among others, the origin of these cells, their phenotypic modulation in vivo and in vitro, their transformation into endothelial cells and the mechanisms of their contribution to neovessels formation. This volume should prove a useful reference for researchers and students alike in the fields of angiogenesis cancer research and haematologic oncology.