Modern Concepts and Methods in Bioenergetics

Modern Concepts and Methods in Bioenergetics examines mitochondrial and cellular bioenergetics, including advances made in understanding the contribution of dysfunctional bioenergetics in the pathogenesis and propagation of various diseases, how to target pathways with novel drugs and metabolites to prevent or treat diseases, and the use of mitochondrial bioenergetic signatures as biomarkers for disease progression. This book highlights methods that have been used to gauge the Mitochondrial Health Index, and also provides novel approaches utilized to identify how mitochondria participate in cellular signaling, serve as a platform for information transmission and act as a sink for intra- and extracellular reactive oxygen species. These topics are discussed along with central themes of mitochondrial bioenergetics and redox biology, factors that are integral for optimal cellular health.