Microdomains in the Cardiovascular System

The cardiovascular system, also referred to as the circulatory system, is integral to the transport of blood, nutrients, oxygen and waste products throughout the body. It comprises the heart, blood vessels and blood. Microdomains in the cardiovascular system are specialized, nanoscale regions within cells that compartmentalize signaling molecules, ion channels, and receptors to regulate local cellular functions. These microdomains, such as caveolae, lipid rafts, and t-tubules, are crucial for processes like calcium handling, signal transduction, and cell communication, particularly in cardiac and vascular smooch muscle cells. By confining specific proteins and enzymes within limited spaces, microdomains enable precise, rapid responses to physiological stimuli, enhancing the efficiency and specificity of cellular signaling pathways critical for cardiovascular function, such as contraction, relaxation, and vascular tone regulation. This book contains some path-breaking studies in the field of microdomains in the cardiovascular system. Such selected concepts that redefine cardiology have been presented in this book. Students, researchers, experts and all associated with cardiology will benefit alike from this book.