Immunodeficiency Disorders and Retroviruses

Advances in Veterinary Science and Comparative Medicine, Volume 32: Immunodeficiency Disorders and Retroviruses provides an understanding of retrovirus morphogenesis, pathogenesis, and the processes of infection and transformation. This book discusses several issues in retrovirology and their importance in basic viral oncology, comparative medicine, veterinary medicine, and immunodeficiency syndromes. Organized into eight chapters, this volume begins with an overview of the replication cycle of retroviruses. This text then summarizes the factors responsible for the progression of the neoplastic condition through each stage in the ontogeny of lymphoid leukosis. Other chapters consider bovine leukemia virus, which is the etiological agent of a chronic lymphatic leukemia/lymphoma in sheep, cos, and goats. This book discusses as well the immunologic, virologic, and epidemiologic aspects of immunosuppressive disease caused by type D retroviruses. The final chapter deals with the involvement of DNA and RNA oncogenic viruses in animal and human neoplasias. This book is a valuable resource for scientists, oncologists, and clinicians.