Gastrointestinal Drug Absorption

Gastrointestinal absorption of a drug is a complex process which involves a series of sub-processes. It is also subject to different variables such as physiological factors and disease states. Passive non-ionic diffusion is the most prominent mechanism that plays a prominent role in the process of drug absorption. The difference in the concentration or the chemical potential across the membrane helps in the process of absorption. The cell membrane incorporates the non-ionized hydrophobic molecules between the long hydrocarbon chains through a dissolution-like process. As a result, the hydrophobic molecules are transferred into the absorptive cell. There are some other mechanisms that play a minor role in drug absorption. These mechanisms include pinocytosis, facilitated transport and passage through membrane pores. This book is compiled in such a manner, that it will provide in-depth knowledge about the mechanism of gastrointestinal drug absorption. A number of latest researches have been included to keep the readers updated with the latest concepts in this area of study. The book is a vital tool for all researching this biological process.