Cytokines in Hemopoiesis, Oncology, and AIDS

The proceedings of the First International Symposium on Cytokines in Hemopoiesis, oncology, and AIDS offer a comprehensive overview on the latest clinical and preclinical advances in the rapidly developing field of cytokines. The network of the hemopoietic growth factors is one first focus of the book. Effects and actions of GM-CSF, G-CSF, M-CSF, Il-3, IL-4, IL-6 and erythropoietin on normal and malignant hemopoietic cells are discussed in several contributions. As a special feature data on stimulation of nonhemopoietic cells are presented. TNF is in the focus of another section of the book. Clinical data are accompanied by an overview on the TNF-receptor and the regulation of its expression. The interferon section of the book provides the latest information on clinical studies on chronic myeloid leukemia, essential thrombocytosis, non-Hodgkin-lymphoma, and gastrointestinal carcinomas. The last section of the book is dedicated to the clinical and preclinical effects of IL2, together with basic overviews on NK-cell regulation and differentiation.