Communications in Computer and Information Science

This book constitutes the proceedings of the First International Joint Conference on Artificial Intelligence for Healthcare, and Hybrid Models for Coupling Deductive and Inductive Reasoning, HC@AIxIA+HYDRA 2025, which took place in Bologna, Italy, during 25-26 October 2025.The 40 full papers included in this book were carefully reviewed and selected from 61 submissions. They were organized in topical sections as follows: Rehabilitation and Human-Robot Interaction; AI for Diagnosis and Medical Imaging; short communications; temporal data modeling and analysis; causal modeling and data reasoning; patient management; neur-symbolic and multi-modal learning; large language models in healthcare; and healthcare applications.