This book explores the rapidly evolving field of nanobiotechnology and its applications in plant health and agricultural sustainability. Focusing on nanomaterials and nano-sensors, the book presents strategies for the detection, diagnosis and management of plant diseases, foodborne pathogens and agricultural pests. Chapters delve into the use of nanodevices for early disease detection, nano-pesticides for targeted treatment and bio-nanosensors for monitoring microbial contaminants in food systems. This book further highlights the role of biogenic and polymeric nanomaterials as effective fertilizers, fungicides and protective agents against plant-parasitic nematodes and microbial infections. This book also addresses critical issues of nanoparticle toxicity and ecological safety, providing a balanced view on the risks and benefits of nanotechnology in agriculture.This edited volume is designed for graduate students, researchers, agronomists, plant pathologists and nanotechnologists. This volume offers practical reference for integrating nanoscience into plant protection systems. It also serves as a guide for policymakers and agri-tech professionals seeking sustainable, high-precision solutions for global food security.