Pathophysiology of Severe Ischemic Myocardial Injury

In industrialized countries, ischemic heart disease is by far the most common organ-specific cause of death. The failure of a heart with an ischemic area may be due to the amount and location of contractile tissue becoming paralyzed or even necrotic, or to arrhythmias provoked by the ischemic condition, or by a combination of both factors.