Drug Resistance

Resistance to treatment represents the final common outcome for far too many patients with cancer. Even promising new drugs fall victim to drug resistance. Hormones and newer biological therapies, though safe and active, also lose their activity over time. In this volume contributors from within the field have reviewed the most basic mechanisms of drug resistance, and have proposed ways to modulate resistance. This comprehensive text should be of use for basic and clinical scientists who wish to delve more deeply into this intriguing problem in the laboratory and devastating problem in the clinic.