Dengue Virus Evolution: From Emergence to a Global Health Crisis

This volume explores dengue’s path from viral emergence to a global health crisis, providing a comprehensive examination of one of the world's most resilient and adaptable arboviruses. The individual chapters, written by leading experts in the field of dengue research, encompass multidisciplinary perspectives and illuminate the intricate dance between the dengue virus, its hosts and its environment. The viral biology and the molecular mechanisms of pathogenesis, its evolution and clinical manifestations are presented in detail. In addition, the volume offers insights into the response of the host immune system to the virus and discusses diagnostics, new vaccines and treatment strategies. In a unique way, the volume explores the link between climate change and the dynamics of virus transmission and shows groundbreaking surveillance methods that help with real-time tracking and prediction of potential outbreaks. This book is aimed at researchers, advanced students and healthcare professionals in academia, industry and public authorities.