Consists of critical reviews and original research papers from the 2014 International Symposium on the "e;Biochemical Role of Eukaryotic Cell Surface Macromolecules"e;. Topics covered include: * neurochemical and biochemical analysis of cell surface glycoconjugates * membrane skeletal organization * GPCRs and other receptors * biophysical approaches to study membrane interactions * glycoconjugate metabolism * dysregulation * molecular mechanisms involved in cell-cell and cell-matrix interaction * glycans in infectious and neurological diseases * cancer and glycosyltransferases as drug targets.