Syntesis, characterization and antimicobial activity of novel imidazoles

Doctoral Thesis / Dissertation from the year 2013 in the subject Chemistry - Organic Chemistry, grade: A-C, Sardar Patel University, language: English, abstract: The condensation reaction of 4-benzylidene-2-phenyloxazol-5-one (2) with 2-amino-4-substitued benzothiazoles (3a-f) was yielded a series of 4-benzylidene-1-(substitued-2-benzothiazolyl)-2-phenyl-1H-imidazol-5(4H)-one (4a-f). The 4-benzylidene-2-phenyloxazol-5-one (2) has been prepared from cyclo condensation reaction between N-benzoyl glycine(1) with benzaldehyde. The novel prepared compounds were characterized by IR, 1H-NMR,13C-NMR and Mass spectral data. All the prepared compounds were screened for their antibacterial and antifungal activities.