On Sulphonfluorescein and Some of Its Derivatives is a scientific treatise authored by Arthur George Green, first published in 1885. This work delves into the chemistry of sulphonfluorescein, a compound related to fluorescein, and explores its various derivatives. The book provides a detailed account of the synthesis, properties, and reactions of sulphonfluorescein, offering insights into its chemical structure and behavior. Green meticulously documents his experimental methods, observations, and results, contributing valuable knowledge to the field of organic chemistry, particularly in the study of dyes and colorants. The text is structured to guide the reader through the historical context of fluorescein research, followed by a comprehensive examination of sulphonfluorescein's preparation and the chemical processes involved in its derivatization. Green discusses the physical and chemical characteristics of the compounds, including their solubility, color changes, and reactions with various reagents. The book also includes comparative analyses with related substances, highlighting the significance of sulphonation in modifying the properties of fluorescein. Intended for chemists and researchers, On Sulphonfluorescein and Some of Its Derivatives stands as a testament to the meticulous experimental work of the late 19th century. It not only advances the understanding of sulphonfluorescein compounds but also serves as a reference for future studies in dye chemistry and the broader field of organic synthesis.