Guide to Techniques in Mouse Development, Part A

Guide to Techniques in Mouse Development, Part A comprehensively covers new technologies and methodologies that have appeared for the study of mouse development. - Update of volume 225 of Methods in Enzymology, Guide to Techniques in Mouse Development, edited by P.M. Wassarman and M.L. DePamphilis and published in 1993- Covers new technologies and methodologies, including:- new techniques for the cryopreservation of gametes and embryos- production of transgenic and null (knockout) animals (use of ES cells)- generation of conditional/inducible mutant animals- use of gene-trap mutagenesis- analysis of allele-specific expresion- use of new reporter constructs- humanizing of transgenic animals- transcript profiling of mouse development- imaging of mouse development- rederivation of animals and use of mouse genomics