The foundational concepts discussed emerge from such fields as neurobiology, cognitive sciences, physics, and organizational theory. These are applied to management and substantiated with examples. New developments in knowledge management, such as connectionist approaches, are outlined and illustrated with real cases. The author further describes an approach for developing knowledge networks in companies. The annex offers readers with an advanced interest in the matter an epistemological discussion on scientific methods for management research and touches in a broader sense on the measurability of management processes.