Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
Drug Metabolism and Pharmacokinetics Quick Guide
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- Författare: Siamak Cyrus Khojasteh Harvey Wong Cornelis E. C. A. Hop
- Språk: Engelska
- Utgiven: 2011-04
- ISBN: 9781441956286
- Förlag: Springer-Verlag New York Inc.
- Upplaga: 1
- Antal sidor: 214
- Vikt: 249 gram
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