The use of intravenous access devices is fundamental for all patients needingfrequent blood sample collection, artificial nutrition, chemotherapy, antibiotictherapy, and any other intravenous treatment. This is important both in hospitaland home settings. The big news in the last ten years has been the introductionof PICC (Peripherally Inserted Central Catheters) and MIDLINE catheters.These intravenous catheters are used by trained physicians and nurses and theinsertion is ultrasound-guided.This manual offers a thorough description of the several clinical settings in whichthese devices are used and provides clear information on the insertion proceduresand management. Also, the authors take into consideration the technicalcharacteristics of the materials, the replacement and removal procedures, aswell as how to effectively prevent complications.