Endogenous and Exogenous Opiate Agonists and Antagonists

Endogenous and Exogenous Opiate Agonists and Antagonists documents the proceedings of the International Narcotic Research Club Conference, held in North Falmouth, Massachusetts, USA, on 11-15 June 1979. The volume begins with a discussion of the programs of the World Health Organization, with an emphasis on the components of its drug dependence program. The 139 papers discussed at the conference are then presented. These papers are organized into 10 parts. The papers in Part I examine structure-activity relationships. Part II contains studies on receptor binding while Part III deals with the localization and characterization of active sites. Part IV focuses on ligands and receptor isolation. Part 5 examines neurochemical interactions. Part VI presents papers on disposition and metabolism. Parts VII and VIII take up analgetic mechanisms and neuroendocrine relationships, respectively. Part IX focuses on behavioral effects while the studies in Part X cover tolerance and physical dependence.