Development of Topical Formulation Containing Permeation Enhancer

In the present study, an attempt was made to prepare, characterize, and evaluate a topical therapeutic system for anti-inflammatory purposes, utilizing a natural permeation enhancer. Various hydrogel formulations were designed and optimized using varying concentrations of carbopol polymer.Natural remedies are often perceived as safer with fewer side effects compared to synthetic ones, thus experiencing a growing demand in the global market. This study aims to demonstrate that natural permeation enhancers in gel formulations exhibit promising permeation enhancement properties.