Cancer Metastasis: Molecular and Cellular Mechanisms and Clinical Intervention

Cancer metastasis is a process wherein cancer cells spread or are transferred to organs and tissues other than the site of primary tumor, leading to the development of new tumors. The capacity to metastasize is a primary feature of malignant tumors. Cancer cell dissemination is modulated by the regulation of specific cellular characteristics, a variety of micro environmental factors. Metastases occur when cancer cells break away from the primary tumor and reach the lymphatic system or the bloodstream. These systems transport fluids throughout the body, indicating that cancer cells can migrate far from the initial tumor site and generate new tumors. The majority of metastatic cancers can be treated, and the objective of treating metastatic cancer is to halt or prevent its progression. This book explores all the molecular and cellular mechanisms, and the clinical interventions related to cancer metastasis. It will prove to be immensely beneficial to students and researchers in this field.