Bacteriophage-Based Vectors in Gene Therapy

Bacteriophages are powerful and versatile tools in genetic medicine. This book explores the innovative historical and current uses of these bacterial viruses to create targeted gene delivery systems, vaccines, and immunotherapeutics. It addresses the urgent need for cost-effective, scalable alternatives to traditional viral vectors by highlighting the transformative potential of phage-based platforms.The book is structured to provide a comprehensive framework for researchers and clinicians, exploring the biological and structural roles of different phage types. It also examines cutting-edge methodologies, including phage display technologies, genomic manipulations, chemical manipulations, hybrid vector development, and biomanufacturing innovations. Through case studies and comparative analyses, it reveals significant advances in vector functionality and therapeutic safety. This essential resource offers solutions to current vector limitations, helping to expand the potential of genetic medicine.