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Pharmacology of Smooth Muscle
Eighty years have passed since Arthur Heffter, the founder of this handbook series, invited in 1913 eminent scientists from different parts of the world to contribute. At that time …
Pharmacology of Asthma
This volume forms part of a prestigious series and covers the latest advances in our understanding of the pathophysiology and treatment of asthma. Our understanding of asthma has …
Opioids II
In 1957 Otto SCHAUMANN, one of the pionieers in pharmacological research on morphine and the first to prepare synthetic opiates, presented a mono graph entitled "Morphin und …
Gastrointestinal Regulatory Peptides
Since the discovery of the pancreatic secretagogue secretin by W. M. BAYLISS and E. H. STARLING at the inception of the twentieth century, intense interest has focused on numerous, …
Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
Advances in molecular biology describing important enzyme systems involved in drug conjugation and deconjugation reactions and recent work indicating the importance of drug and …
The Pharmacology of Monoclonal Antibodies
It has been almost 20 years since the discovery by Kohler and Milstein of the technology to produce monoclonal antibodies (MAbs), a discovery that promised revolutionary changes in …
Antimalarial Drug II
The construction of this volume has been guided by two personal convictions. Experience in the field of experimental chemotherapy, both in the pharmaceutical industry and academia, …
Physiology and Pharmacology of the Blood-Brain Barrier
The blood-brain barrier is still not completely understood and therefore the subject of fascinating study. How are endogenous substances transported through the blood-brain …
GTPases in Biology II
Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches uti- lized intracellularly in biological systems. The origins of …
Experimental Production of Diseases: Heart and Circulation
Toxicology of Metals
The toxicology of metals has been concerned in the past with effects that produced clinical signs and symptoms. However, this view of metal toxicology has expanded in recent years …