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Pharmacology and Therapeutics of Asthma and COPD
The aim of the book is to provide an in-depth review of our current understanding of the pathogenesis of both asthma and COPD. This volume also discusses the promising new options …
Circadian Clocks
This book provides the reader with a contemporary and comprehensive overview about the molecular, cellular and system-wide principles of circadian clock regulation. Emphasis is …
Mammalian Transient Receptor Potential (TRP) Cation Channels
In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. …
The Vascular Endothelium II
This wide ranging work provides a complete representation of the present state of knowledge of the vascular endothelium. The volume comprises 20 chapters by experts who have made …
Antidepressants: Past, Present and Future
This book is being published as we mark the end of the first 50 years of the modern antidepressant era. This era began with the chance discovery that tri- clic antidepressants and …
Neurotrophic Factors
This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, …
Angiotensin Vol. I
Nearly thirty years ago, in 1974, the volume on Angiotensin edited by Irvine H.Page and F. Merlin Bumpus expanded the Handbook of Experimental Pharmacology. Even after two decades …
Principles of Safety Pharmacology
This book illustrates, in a comprehensive manner, the most current areas of importance to Safety Pharmacology, a burgeoning unique pharmacological discipline with important ties to …
Nitric Oxide
Nitric oxide (NO) has been discovered to play a fundamental role in a number of biological phenomena. This book describes various aspects of nitric oxide biology, physiology and …
Ionotropic Glutamate Receptors in the CNS
It is now widely accepted that glutamate is the major excitatory neurotrans- mitter in the mammalian central nervous system. The main criteria for accept- ing a molecule as a …
Histone Deacetylases: the Biology and Clinical Implication
The book highlights work from many different labs that taught us abnormal HDACs potentially contribute to the development or progression of many human diseases including immune …