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Fluorine In Pharmaceutical And Medicinal Chemistry: From Biophysical Aspects To Clinical Applications
Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging …
Merkel Cell Carcinoma: A Multidisciplinary Approach
Merkel cell carcinoma is an uncommon but not rare aggressive cutaneous malignancy. It has many similarities to melanoma, particularly in the need for aggressive multidisciplinary …
Molecular Exploitation Of Apoptosis Pathways In Prostate Cancer
This book focuses on the functional significance of targeting apoptosis for the treatment of prostate cancer. New concepts on the challenges relating to the development of …
Antibody Drug Discovery
Monoclonal antibodies have become important treatments for cancer, inflammation and a wide range of other diseases, representing an increasing share of the most successful …
Micrornas In Development And Cancer
MicroRNAs have recently emerged as key regulators of gene expression during development and are frequently misexpressed in human disease states, in particular cancer. These …
Dna Deamination And The Immune System: Aid In Health And Disease
This book covers the current understanding of the role of activation-induced cytidine deaminase (AID) in the generation of antibody response to antigenic challenge. Since the …
Alzheimer's Disease: Insights Into Low Molecular Weight And Cytotoxic Aggregates From In Vitro And Computer Experiments - Molecular Basis Of Amyloid-beta Protein Aggregation And Fibril Formation
Alzheimer's disease is the most common form of senile dementia, affecting more than 24 million people worldwide. It is characterised pathologically by abnormally high levels of …