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Pharmacology of Smooth Muscle
Eighty years have passed since Arthur Heffter, the founder of this handbook series, invited in 1913 eminent scientists from different parts of the world to contribute. At that time …
The Pharmacology of Monoclonal Antibodies
It has been almost 20 years since the discovery by Kohler and Milstein of the technology to produce monoclonal antibodies (MAbs), a discovery that promised revolutionary changes in …
Chemotherapy of Viral Infections
" . . . the motto for the therapeutics of the future will have to be de sedibus et causis pharmacorum. " P. EHRLICH, 1909 Exciting events in the basic disciplines of virology, …
Heme and Hemoproteins
The study of the biological effects of foreign chemicals (whether therapeutic drugs or chemicals present at work or in the environment) interests the biologist from a number of …
Physiology and Pharmacology of the Blood-Brain Barrier
The blood-brain barrier is still not completely understood and therefore the subject of fascinating study. How are endogenous substances transported through the blood-brain …
GTPases in Biology II
Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches uti- lized intracellularly in biological systems. The origins of …
Catecholamines II
Catecholamines are important transmitter substances in the autonomic and central nervous systems. These two volumes provide a comprehensive presentation of the state-of-the-art of …
Toxicology of Metals
The toxicology of metals has been concerned in the past with effects that produced clinical signs and symptoms. However, this view of metal toxicology has expanded in recent years …
The Pharmacology of Alcohol Abuse
In recent years alcohol abuse has received increased international attention. Such attention is justified by the enormous negative impact that this disorder has on health, as well …
Pharmacokinetics of Drugs
The author of this Foreword has recently retired after spending 25 years in academia and 15 years in the pharmaceutical industry. Most of this time has been spent following and, …
Antimalarial Drugs I
Of all the parasitic diseases that beset man in the warmer parts of the world, malaria is still the major cause of morbidity and mortality. In spite of intensive efforts to …