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Decoding the Genomic Control of Immune Reactions
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of …
Stem Cells
Understanding stem cells at the molecular level is essential to understanding their behaviour in a physiological context. This volume in our acclaimed Novartis Foundation series …
Retinal Dystrophies
Retinal dystrophies are the major causes of incurable blindness in the Western world. Our insight into their aetiology has improved remarkably over the past decade and a number of …
Chronic Fatigue Syndrome
Documents the latest results and opinions on the causes and possible cures for this disorder. Coverage includes retroviral involvement, immunity, pathophysiology and …
Photosensitizing Compounds
Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and …
Molecular Control of Haemopoiesis
The many different kinds of blood cells found in the human body are derived from multi-potential stem cells, which are induced to differentiate into one or another cell type by the …
Fatty Acid and Lipotoxicity in Obesity and Diabetes
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure …
Molecular Basis of Cellular Defence Mechanisms
The field of lymphokine research has grown in parallel to the exciting developments around the two sets of cells which defend the body. While lymphokines are the …
Environmental Statistics
Environmental statistics is a rapidly growing discipline that is important not only as a division of professional and academic statistics, but also in the accumulation of data on …
Environmental Change and Human Health
Discusses those aspects of environmental change which might have direct or indirect effects on human health. Includes discussions on water pollution, agricultural pollution, …
Immunological Tolerance
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell …