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The Olympics that Never Happened
A look back at how powerful politicians, business leaders, and a diverse cast of activists used a thwarted Olympics to shape the state of Colorado and the city of Denver. If you …
Modelling Climate Change Impacts on Agricultural Systems
Climate change is a key threat to agriculture. Modelling is fundamental to assessing its potential impacts. This collection summarises the wealth of research on improving climate …
Genome-Based Diagnostics
Genome-Based Diagnostics: Demonstrating Clinical Utility in Oncology is the summary of a workshop convened in May 2012 by the Roundtable on Translating Genomic-Based Research for …
Generating Evidence for Genomic Diagnostic Test Development
Ten years after the sequencing of the human genome, scientists have developed genetic tests that can predict a person's response to certain drugs, estimate the risk of developing …
Economics of Genomic Medicine
The sequencing of the human genome and the identification of links between specific genetic variants and diseases have led to tremendous excitement over the potential of genomics …
Drug Repurposing and Repositioning
Drug development can be time-consuming and expensive. Recent estimates suggest that, on average, it takes 10 years and at least $1 billion to bring a drug to market. Given the time …
Improving the Efficiency and Effectiveness of Genomic Science Translation
The process for translating basic science discoveries into clinical applications has historically involved a linear and lengthy progression from initial discovery to preclinical …
Genome-Based Diagnostics
The sequencing of the human genome and the identification of associations between specific genetic variants and diseases have led to an explosion of genomic-based diagnostic tests. …
Economics of Genomic Medicine
The sequencing of the human genome and the identification of links between specific genetic variants and diseases have led to tremendous excitement over the potential of genomics …
Introduction to Tornado
Tornado is a scalable, non-blocking web server and web application framework written in Python. It is also light-weight to deploy, fun to write for, and incredibly powerful. …
ExoFrontiers
Stem Cell Therapies
Stem cells offer tremendous promise for advancing health and medicine. Whether being used to replace damaged cells and organs or else by supporting the body's intrinsic repair …