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totalt 31 träffar
Regulation of Endothelial Barrier Function
The vascular endothelium lining the inner surface of blood vessels serves as the first interface for circulating blood components to interact with cells of the vascular wall and …
Control of Cardiac Output
Although cardiac output is measured as the flow of blood from the left ventricle into the aorta, the system that controls cardiac output includes many other components besides the …
The Enteric Microbiota
The human gut is the natural habitat for a diverse and dynamic microbial ecosystem having an important impact on health and disease. Bacteria have lived in and on animal hosts …
Platelet-Vessel Wall Interactions in Hemostasis and Thrombosis
Platelets are essential mediators of the physiologic process of hemostasis and pathologic thrombosis. While platelets do not interact with vascular walls under normal conditions, …
Heme Oxygenase and the Kidney
Heme oxygenases (HOs) are the enzymes responsible for the breakdown of heme and the generation of biliverdin/bilirubin and carbon monoxide (CO). The kidney is a complex organ …
Regulation of Vascular Smooth Muscle Function
Vascular smooth muscle (VSM) constitutes most of the tunica media in blood vessels and plays an important role in the control of vascular tone. Ca2+ is a major regulator of VSM …
The Gastrointestinal Circulation
The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone …
Skeletal Muscle Circulation
The aim of this treatise is to summarize the current understanding of the mechanisms for blood flow control to skeletal muscle under resting conditions, how perfusion is elevated …
Intestinal Water and Electrolyte Transport
The unique architecture and physiology of the mammalian intestine, together with a tightly coordinated regulatory system, allows for the handling and absorption of as much as 9 L …
Intestinal Immune System
In the intestine, a unique immunological system that is different from the systemic immune system exists to provide adaptive immunity in response to luminal bacteria and dietary …
Local Control of Microvascular Perfusion
Local control of microvascular perfusion refers to the ability of individual tissues to maintain a relative constancy of hemodynamics in the face of changing perfusion pressure …
Alveolar Structure and Function
In the distal regions of the human lung, one of the most challenging problems facing a large multicellular organism is solved—ensuring an adequate supply of oxygen for aerobic …