For the selection the Editor focussed on three key syntheticapproaches with the greatest impact:
1. Use of silicon as a 'temporary tether' by unifying a reactivepair of functional groups and taking advantage of theirtemplate-biased intramolecular cyclization.
2. The specific use of the silane functionality as a heterot-butyl group, often colloquially referred to as the use ofsilicon as a 'fat proton'.
3. The use of the Brook rearrangement as an 'anion relaystratagem'.
A new feature in this Handbook is the reagent finder, analphabetically organized lookup table arranged by organicfunctionality and specific structure of the silicon atom to whichit is bound.