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Neurodegeneration in Multiple Sclerosis
In multiple sclerosis (MS), conventional magnetic resonance imaging (cMRI) has proved to be a valuable tool to increase diagnostic confidence and for monitoring the efficacy of …
Magnetic Resonance Techniques in Clinical Trials in Multiple Sclerosis
We have entered an exciting period in the study of multiple sclerosis and its treatment. Central to this progress has been the introduction of magnetic reso nance techniques. When …
New Frontiers of MR-based Techniques in Multiple Sclerosis
In the past few years there have been impressive advances in the implementation of modern MRI techniques for the assessment of MS patients with the ultimate goal to define MRI …
Primary Progressive Multiple Sclerosis
"Why are there no effective treatments for my condition? Why do researchers exclude patients with primary progressive multiple sclerosis from enrolling in clinical trials? Please …
Early Indicators Early Treatments Neuroprotection in Multiple Sclerosis
There is now evidence that irreversible brain damage accumulates very early in the course of multiple sclerosis. This book reviews the main neurobiological, magnetic resonance …
Magnetic Resonance Spectroscopy in Multiple Sclerosis
Recent years have witnessed dramatic advances in the development and use of magnetic resonance imaging (MRI) techniques that can provide quantitative measures with some degree of …
Normal-appearing White and Grey Matter Damage in Multiple Sclerosis
In the last few years, increasing effort has been devoted to better define the characteristics of tissue damage occurring outside MRI-visible lesions in patients with multiple …