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Evaluation of Drug Candidates for Preclinical Development
Emphasizes the integration of major areas of drug discovery and their importance in candidate evaluation It is believed that selecting the "right" drug candidate for development is …
Drug Design of Zinc-Enzyme Inhibitors
Brings together functional and structural informationrelevant to the design of drugs targeting zinc enzymes The second most abundant transition element in living organisms, zinc …
Plant Bioactives and Drug Discovery
An in-depth exploration of the applications of plant bioactive metabolites in drug research and development Highlighting the complexity and applications of plant bioactive …
Carbohydrate Recognition
This book contains contributions from interdisciplinary scientists to collectively address the issue of targeting carbohydrate recognition for the development of novel therapeutic …
Kinase Inhibitor Drugs
A comprehensive resource on case studies of marketed kinase drugs and promising drug trials Since the discovery of protein kinase activity in 1954, the field of protein kinase …
Medicinal Chemistry of Nucleic Acids
Complete, up-to-date coverage of the broad area of nucleic acid chemistry and biology Assembling contributions from a collection of authors with expertise in all areas of nucleic …
Cyclic-Nucleotide Phosphodiesterases in the Central Nervous System
This book reviews advances in understanding phosphodiesterases within the central nervous system and their therapeutic applications. A range of expert authors from both academia …
Chemosensors
A thorough, accessible, and general overview of chemosensors Providing a comprehensive overview of chemosensors?organic molecules designed to bind and sense small molecules or …
Drug Delivery
Following its successful predecessor, this book covers the fundamentals, delivery routes and vehicles, and practical applications of drug delivery. In the 2nd edition, almost all …
HIV-1 Integrase
This book comprehensively covers the mechanisms of action and inhibitor design for HIV-1 integrase. It serves as a resource for scientists facing challenging drug design issues and …
Glycogen Synthase Kinase 3 (GSK-3) and Its Inhibitors
Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some …
Computer Applications in Pharmaceutical Research and Development
A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of …