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Pharmaceutical Salts and Co-crystals
From crystal structure prediction to totally empirical screening, the quest for new crystal forms has become one of the most challenging issues in the solid state science and …
Drug Discovery from Natural Products
This book offers an integrated review of the most recent trends in natural products drug discovery and key lead candidates that are outstanding for their chemistry and biology as a …
Venoms to Drugs
1. Gives an overview of the development of drugs from peptides and proteins present in venom.2. Six drugs derived from venoms have already been approved, and there are many more in …
New Therapeutic Strategies for Type 2 Diabetes
The diabetes mellitus epidemic is unfolding across the globe with the World Health Organization (WHO) reporting a worldwide prevalence of 177 million patients with diabetes. Type 2 …
Macrocycles in Drug Discovery
This book reviews macrocycles in drug discovery, both those of natural origin and semi-synthetic derivatives of natural products, and those designed and synthesized based on …
Emerging Drugs and Targets for Alzheimer's Disease
Alzheimer's disease is the most prevalent neurodegenerative disorder in the elderly. A recent study from the Bloomberg School of Public Health recently estimated that over 26 …
Biomarkers for Traumatic Brain Injury
Due to injuries sustained in sports and in combat, interest in TBI has never been greater. Biomarkers for Traumatic Brain Injury will fulfil a gap in our understanding of what is …
Neglected Diseases and Drug Discovery
There are about 8 million deaths each year from neglected tropical diseases (NTDs) in the underdeveloped world, whilst drug discovery focus and practice is only recently taking on …
Physico-Chemical and Computational Approaches to Drug Discovery
Molecular modeling and simulation play a central role in academic and industrial research focused on physico-chemical properties and processes. The efforts carried out in this …
Kinase Drug Discovery
Kinase drug discovery remains an area of significant interest across academia and in the pharmaceutical industry. There are now around 13 FDA approved small molecule drugs which …
New Synthetic Technologies in Medicinal Chemistry
The modern synthetic chemist applies all the tools available to identify the drug-like molecules with the best chances of becoming novel drugs. This book will act as a primer for …
Human-based Systems for Translational Research
This book provides a history and discussion of the use of human tissues as an alternative to animal-based testing for assessing the efficacy and safety of new medicines. Beginning …