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Gastrointestinal Regulatory Peptides
Since the discovery of the pancreatic secretagogue secretin by W. M. BAYLISS and E. H. STARLING at the inception of the twentieth century, intense interest has focused on numerous, …
Conjugation—Deconjugation Reactions in Drug Metabolism and Toxicity
Advances in molecular biology describing important enzyme systems involved in drug conjugation and deconjugation reactions and recent work indicating the importance of drug and …
Pharmacology of Smooth Muscle
Eighty years have passed since Arthur Heffter, the founder of this handbook series, invited in 1913 eminent scientists from different parts of the world to contribute. At that time …
Antimalarial Drug II
The construction of this volume has been guided by two personal convictions. Experience in the field of experimental chemotherapy, both in the pharmaceutical industry and academia, …
Heme and Hemoproteins
The study of the biological effects of foreign chemicals (whether therapeutic drugs or chemicals present at work or in the environment) interests the biologist from a number of …
Hypolipidemic Agents
The major cause of death in the Western world is some form of vascular disease; and principal among these forms is atherosclerotic heart disease (ASHD). Although much is known …
GTPases in Biology II
Recent advances in molecular biology have shown GTPases and phosphoproteins to be the paramount molecular switches uti- lized intracellularly in biological systems. The origins of …
Experimental Production of Diseases: Heart and Circulation
Toxicology of Metals
The toxicology of metals has been concerned in the past with effects that produced clinical signs and symptoms. However, this view of metal toxicology has expanded in recent years …
The Pharmacology of Alcohol Abuse
In recent years alcohol abuse has received increased international attention. Such attention is justified by the enormous negative impact that this disorder has on health, as well …
Cyclic Nucleotides
The purpose of the present volume, the first of two on the pharmacology, biochemistry, and physiology of cyclic nucleotides, is to provide a comprehensive and up-to-date anthology …