This book is a tribute to Professor Yuan-Cheng Fung, the Father of Biomechanics and a pioneer in Bioengineering, in honor of his 90th Birthday. The book consists of articles contributed by his colleagues, students, friends and family. These articles illustrate Professor Fung's profound influence on outstanding leaders in bioengineering, especially biomechanics, and on the life and work of all people who have been in contact with him. The scientific topics covered range from fundamentals of science and engineering (e.g., residual stress, flow dynamics, and cellular signaling) to clinical disorders (e.g., atherosclerosis, diabetes, and hypertension). The articles cover the whole spectrum of biological hierarchy, from genes/molecules to cells/tissues, and organs/systems, with close correlations between engineering and biomedical sciences. This book provides an excellent view of the marvelous contributions of Professor Fung as a Renaissance Man.Contents:Physical Mechanisms of Soft Tissues Rheological Properties (Y Lanir)Biomechanics of an Isolated Single Stress Fiber (M Sato & S Deguchi)The Origin of Pre-Stress in Biological Tissues — A Mechano-Electrochemical Model: A Tribute to Professor Y-C Fung (L Q Wan et al.)How Blood Flow Shapes Neointima (S Q Liu & Y C Fung)Illuminating a Path: Role of Biomechanics in Understanding Adaptive Remodeling in the Microcirculation (T C Skalak)Computational Simulations of the Buckling of Oval and Tapered Arteries (A Northcutt et al.)Role of Structural and Signaling Molecules in Cardiac Mechanotransduction (A M Raskin et al.)A Novel Hemodynamic Analysis of Echocardiograms (T-K Hung)In Vitro Biomechanical Studies in Aging Human Lungs (S Majd & M Yen)Modeling the Oxygen Uptake in Pulmonary Alveolar Capillaries (C-J Chuong)Two Bioengineering Solutions for a Pulmonary Circulation (J B West)Fluid Flow Induced Calcium Response in Bone Cell Network (B Huo et al.)Analysis of the Models for Cytoskeletal Rheology (R D Kamm et al.)Y-C Fung and the Biomechanics of Hearing (R Z Gan)A Model for a Class of Diffusion-Based Intercellular Communication (S Nemat-Nasser & A V Amirkhizi)Stem Cells, Biomechanics, and Y C Fung (T Ashan et al.)Of Mice and Men … And a China Connection (D P Giddens et al.)Multi-Patient FSI Studies for Atherosclerotic Carotid Plaque Progression Based on Serial Magnetic Resonance Imaging (D-L Tang et al.)Current Status on Countermeasures for Intradialytic Hypotension (J-S Lee)Pressure Ulcer, Pressure and Flow Motion (Z-Y Lee et al.)and other Tribute articlesReadership: Academics and research scientists in the field of bioengineering, mechanical engineering and biomedical disciplines, scientists in industry, government and other institutions, and the general public.