When Emperor Zombie threatens the safety of all life on earth, President Lincoln enlists the aid of a mechanical head. With the help of associates Mr. Groin (a faithful manservant) and Mr. Dog (a dog), Screw-On Head must brave ancient tombs, a Victorian flying apparatus, and demons from a dimension inside a turnip. This new collection of oddball Mignola creations also includes "The Magician and the Snake" from Dark Horse Maverick: Happy Endings and nearly fifty pages of brand-new material, all as weird and hilarious as the beloved Screw-On Head.
- The Amazing Screw-On Head won an Eisner Award for Best Humor Publication.
- "The Magician and the Snake" won an Eisner Award for Best Short Story.
- The Amazing Screw-On Head was the source for the cult animated short starring Paul Giamatti, David Hyde Pierce, and Patton Oswalt.