Cytokines are proteins that control communication between cells and they are important in immunity, inflamation, tissue development, tissue repair, and cancer. This book is the new, revised edition of "Cytokines: A Practical Approach" published in 1991. It provides detailed, up-to-date practical information for the study of cytokines and cytokine-like activity and is also a guide to identifying and characterizing individual cytokines and provides a review of cytokine biology. In addition, in providing a guide to some of the most useful techniques in cell and molecular biology, immunology, and biochemistry, it will be useful to workers in many different disciplines of biomedical research. In this second edition, many important new techniques have been added including methods for developing cytokine transgenic mice, measuring soluble cytokine receptors, and assays for newly discovered cytokines (up to 1L-14). Each chapter has been updated in line with current experiments.