Hakutulokset: Sarja cold spring harbor perspectives in biology
yhteensä 12 hakutulosta
Endocytosis
During endocytosis, extracellular molecules and plasma membrane components are selectively internalized by cells. This fundamental process of "cellular ingestion" is required for …
Germ Cells
In sexually reproducing organisms, germ cells give rise to gametes and serve as the link between generations. A key event during germ cell development is the decision to leave …
The Origin and Evolution of Eukaryotes
All protists, fungi, animals, and plants on Earth are eukaryotes. Their cells possess membrane-bound organelles including a nucleus and mitochondria, distinct cytoskeletal …
Wnt Signaling
Wnt proteins are signaling molecules that play critical roles during embryonic development and in the regeneration of adult tissues. They bind to Frizzled and LRP family receptors …
DNA Replication
DNA replication is essential for the propagation of life on Earth. Cells in living organisms must be able to synthesize a complete copy of their DNA with extraordinary precision, …
Protein Synthesis and Translational Control
The synthesis of proteins by ribosomes is a fundamental cellular process. Cells must tightly control protein synthesis to maintain homeostasis and regulate proliferation, growth, …
Signaling by Receptor Tyrosine Kinases
Receptor tyrosine kinases are cell-surface receptors that respond to numerous hormones and growth factors, including insulin, insulin-like growth factors, epidermal growth factor, …
The Endoplasmic Reticulum
The endoplasmic reticulum (ER) is an extensive network of membranes that folds, modifies, and transports proteins in eukaryotic cells. It also manufactures lipids and interacts …
Immune Tolerance
Immune tolerance ensures that the immune system responds to foreign molecules and not to self-molecules. When tolerance breaks down, severe, self-destructive diseases such as …
Symmetry Breaking in Biology
Symmetry breaking events are critical for the survival of living systems. They are required for cell division, development, and movement in all organisms from single-celled species …