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The Human Genome
In February 2001, two separate teams published the first working drafts of the entire human genome, marking an achievement that is certainly one of the seminal developments in our …
Immunotherapy in 2020
This volume features contributions from participants of the ESRF symposium on Immunotherapy in 2020--Visions and Trends for Targeting Inflammatory Diseases held in Potsdam near …
Sex Steroids and the Cardiovascular System
Evidence accumulated over the past decade show that gonadal steroid hormones participate in an important way in the physiological and pa thophysiological regulation of the …
Advances in Eicosanoid Research
Over the last few years, we have witnessed tremendous progress in the field of eicosanoids and their therapeutic applications. Receptor an tagonists for leukotrienes have been …
Apoptosis in Hormone-Dependent Cancers
It is now widely accepted that cells have the ability to initiate a program of gene-directed death, a process called "apoptosis" which may also be used as an innovative strategy …
The Role of Natural Products in Drug Discovery
Natural Products have been important sources of useful drugs from prehistoric times to the present. This book gives an overview about this field and provides important recent …
Organ-Selective Actions of Steroid Hormones
Steroids regulate differentiation, growth and functioning of many tissues via a nuclear receptor gene activation mechanism. Molecular biology has opened the way for more detailed …
Cellular Therapy
The use of cells for the treatment of a variety of diseases is no longer a dream. Today, blood transfusion, bone marrow transplantation, the use of ex vivo cultured skin in wound …
Recent Trends in Molecular Recognition
Reasoning in terms of molecular recognition may be traced back to Emil Fischer, who practiced the art of chemistry at Humboldt University in Prussian Berlin a century ago. Today, …
Novel Approaches to Treatment of Osteoporosis
Osteoporosis affects a growing number of the population. Current treatments are based on prevention of further bone loss after the condition is diagnosed, often because a fracture …