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Chikungunya Virus
This book provides readers with a collection of latest reviews written by Chikungunya virus (CHIKV) research leaders who cover topics related to CHIKV replication, advances in …
Type IV Secretion in Gram-Negative and Gram-Positive Bacteria
Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a …
Global Catastrophic Biological Risks
This volume focuses on Global Catastrophic Biological Risks (GCBRs), a special class of infectious disease outbreaks or pandemics in which the combined capacity of the world’s …
C-Type Lectins in Immune Homeostasis
This book focuses on C-type lectin receptors, a newly emerging family of pattern-recognition receptors (PRRs) and a crucial part of the human innate immune system. Above all, the …
Three Dimensional Human Organotypic Models for Biomedical Research
This edited volume discusses the application of very diverse human organotypic models in major areas of biomedical research. The authors lay a main focus on infectious diseases, …
HIV-1 Latency
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to …
Vaccination Strategies Against Highly Variable Pathogens
Vaccines against antigenically stable pathogens, or pathogens that only exist in a limited number of serotypes, have been very successful in the past and have drastically decreased …
Bacterial Type III Protein Secretion Systems
One of the most exciting developments in the field of bacterial pathogenesis in recent years is the discovery that many pathogens utilize complex nanomachines to deliver …
The Fungal Cell Wall
This book illustrates, that the fungal cell wall is critical for the biology and ecology of all fungi and especially for human fungal pathogens. Readers will learn, that the …
Fungal Extracellular Vesicles
This book provides an in-depth overview on the manifold functions of fungal extracellular vesicles (EV) which span from cell-to-cell communication, pathogenicity and stimulation of …
Inducible Lymphoid Organs
This book sheds new light on “inducible” lymphoid organs (ILOs): antigen presentation sites that are generated de novo in peripheral tissues under various pathogenic conditions. …
Nanoparticles for Rational Vaccine Design
This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles …