The Molecules Online Annual summarizes the papers published in 1997 and 1998 in Molecules Online on the Internet. All electronic features are included on the CD-ROM. Molecules Online is a journal of synthetic organic and natural product chemistry. It is published monthly as an online-journal, with a yearly printed and CD-ROM version. It endeavors to expedite publication electronically with color being offered free of charge. Since Graphical Abstracts of papers published in Molecules Online will be accessible on the internet, authors will have an opportunity to share their research results on a worldwide basis within a short period of time from submission and acceptance of their manuscripts. Abstracts of papers published in Molecules Online will appear in Chemical Abstracts (CAS); it will be indexed in the Science Citation Index.