Kliniska läkemedelsprövningar
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The growing interest in using combination drugs to treat various complex diseases has spawned the development of many novel statistical methodologies. The theoretical development, …
The aim of this book is to equip biostatisticians and other quantitative scientists with the necessary skills, knowledge, and habits to collaborate effectively with clinicians in …
Is adaptive randomization always better than traditional fixed-schedule randomization? Which procedures should be used and under which circumstances? What special considerations …
Get Up to Speed on Many Types of Adaptive DesignsSince the publication of the first edition, there have been remarkable advances in the methodology and application of adaptive …
An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment’s efficacy. When a true endpoint is difficult to …
This is a cohesive and comprehensive book on statistical omics from a biopharmaceutical perspective which focuses on presenting statistical methods, including false discovery rate …
This book focuses on innovative designs that are easy to understand, easy to implement and conceptually intuitive. The author includes methods he recently developed plus ideas and …