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Nutrition and Epigenetics
Nutrition and Epigenetics presents new information on the action of diet and nutritional determinants in regulating the epigenetic control of gene expression in health and disease. …
Inflammation, Lifestyle and Chronic Diseases
Oxidative stress and inflammation are among the most important factors of disease. Chronic infections, obesity, alcohol and tobacco usage, radiation, environmental pollutants, and …
Mitochondrial Dynamics
Mitochondria are among the most important of eukaryotic cell organelles, often referred to as the "powerhouse" of the cell, because of the role they play in providing energy for …
Hormesis in Health and Disease
Some mild stresses have positive effects on survival and aging as shown in animal models. There is also a large body of research that demonstrates these hormetic effects on aging, …
Oxidative Stress and Age-Related Neurodegeneration
Despite the progress being made by researchers, Alzheimer’s disease, along with other age-related neurodegenerative disorders, continues to exact a tremendous toll on our society. …
Dietary Modulation of Cell Signaling Pathways
A consequence of rapid progress in the science of nutrigenomics and nutrigenetics is the substantial accumulation of data covering nutrienal modulation of gene expression at the …
Micronutrients and Brain Health
Micronutrients and Brain Health addresses cutting-edge research related to processes of oxidative stress that affect brain function, an area of increasing significance for those …
Lipid Oxidation in Health and Disease
Oxidative modification of lipids and phospholipids—including radical damage, halogenation, and nitration—result in significant changes to the chemical properties of the molecules, …
Mammalian Heme Peroxidases
Mammalian heme peroxidase enzymes play a critical role in innate immune responses and disease prevention. The formation of potent chemical oxidants is essential to this protective …
Hydrogen Peroxide Metabolism in Health and Disease
Much of the biology of oxidative stress and oxidative signalling centres on the generation and handling of hydrogen peroxide. The overall aim for this book would be to provide an …
Physiological Consequences of Brain Insulin Action
The brain is crucial for the regulation of whole-body metabolism and behavior. The pancreas-derived hormone insulin modulates brain function and affects energy metabolism as well …
Biomedical Application of Nanoparticles
Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system …